Soluble Liver/Pancreas Antigen Antibody

Images

 
Western Blot: Soluble Liver/Pancreas Antigen Antibody [NBP2-20454] - Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE gel, diluted at 1:5000.
Immunohistochemistry-Paraffin: Soluble Liver/Pancreas Antigen Antibody [NBP2-20454] - Paraffin-embedded colon carcinoma. SLA/LP antibody dilution: 1:500

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Soluble Liver/Pancreas Antigen Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human SLA/LP. The exact sequence is proprietary.
Localization
Cytoplasm
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SEPSECS
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:10000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 20% Glycerol, 1% BSA
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for Soluble Liver/Pancreas Antigen Antibody

  • EC 2.9.1.2
  • EC 2.9.1.n1
  • Liver-pancreas antigen
  • LPDKFZp434B1417
  • MGC161491
  • O-phosphoseryl-tRNA(Sec) selenium transferase
  • Sec synthase
  • Selenocysteine synthase
  • Selenocysteinyl-tRNA(Sec) synthase
  • Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
  • SepSecS
  • Sep-tRNA:Sec-tRNA synthase
  • SLA/LP autoantigen
  • SLA/LP
  • SLA-p35
  • SLAUGA suppressor tRNA-associated protein
  • Soluble liver antigen
  • soluble liver antigen/liver pancreas antigen
  • tRNA(Ser/Sec)-associated antigenic protein
  • TRNP48

Background

The 21st amino acid, selenocysteine (sec), is distinct from other amino acids because it lacks its own tRNA synthetase and is the only amino acid synthesized on its cognate tRNA. Synthesis of sec begins with acylation of tRNA(sec) (TRSP; MIM 165060) by seryl-tRNA synthetase (SARS; MIM 607529) to give ser-tRNA(sec), which is subsequently phosphorylated by O-phosphoseryl-tRNA kinase (PSTK; MIM 611310) to give O-phosphoseryl-tRNA(sec). SEPSECS catalyzes the final step of sec synthesis by converting O-phosphoseryl-tRNA(sec) to selenocysteinyl-tRNA(sec) using selenophosphate as the selenium donor (Palioura et al., 2009 [PubMed 19608919]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Bioinformatics

Gene Symbol SEPSECS
Uniprot