Soluble Liver/Pancreas Antigen Products

Description

The 21st amino acid, selenocysteine (sec), is distinct from other amino acids because it lacks its own tRNA synthetase and is the only amino acid synthesized on its cognate tRNA. Synthesis of sec begins with acylation of tRNA(sec) (TRSP; MIM 165060) by seryl-tRNA synthetase (SARS; MIM 607529) to give ser-tRNA(sec), which is subsequently phosphorylated by O-phosphoseryl-tRNA kinase (PSTK; MIM 611310) to give O-phosphoseryl-tRNA(sec). SEPSECS catalyzes the final step of sec synthesis by converting O-phosphoseryl-tRNA(sec) to selenocysteinyl-tRNA(sec) using selenophosphate as the selenium donor (Palioura et al., 2009 (PubMed 19608919)).(supplied by OMIM)

Bioinformatics

Product By Gene ID

51091

Alternate Names

EC 2.9.1.2 EC 2.9.1.n1 Liver-pancreas antigen LPDKFZp434B1417 MGC161491 O-phosphoseryl-tRNA(Sec) selenium transferase Sec synthase Selenocysteine synthase Selenocysteinyl-tRNA(Sec) synthase Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase SepSecS Sep-tRNA:Sec-tRNA synthase SLA/LP autoantigen SLA/LP SLA-p35 SLAUGA suppressor tRNA-associated protein Soluble liver antigen soluble liver antigen/liver pancreas antigen tRNA(Ser/Sec)-associated antigenic protein TRNP48

Research Areas for Soluble Liver/Pancreas Antigen

Find related products by research area and learn more about each of the different research areas below.

Immunology