SOAT 2 Antibody (OTI2D3) [Alexa Fluor™ Plus 488]

• Reactivity: Hu
• Applications: IHC
• Clone: OTI2D3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 488

SOAT 2 Antibody (OTI2D3) [Alexa Fluor™ Plus 488] Summary

• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-120 of human SOAT2 (NP_003569) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SOAT2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SOAT 2 Antibody (OTI2D3) [Alexa Fluor™ Plus 488]

• ACACT2
• ACACT2MGC116732
• ACAT2
• ACAT-2
• ACAT2ARGP2
• acyl Co-A: cholesterol acyltransferase 2
• acyl coenzyme A:cholesterol acyltransferase 2
• acyl-CoA:cholesterol acyltransferase 2
• Acyl-coenzyme A:cholesterol acyltransferase 2
• Cholesterol acyltransferase 2
• EC 2.3.1.26
• SOAT 2
• SOAT2
• sterol O-acyltransferase 2

Background

Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SOAT2