SLITRK1 Antibody

Images

 
Western Blot: Slitrk1 Antibody [NBP1-49541] - Analysis of Slitrk1 in mouse brain lysate.
Immunohistochemistry: Slitrk1 Antibody [NBP1-49541] - Analysis of Slitrk1 in mouse prostate
Western Blot: Slitrk1 Antibody [NBP1-49541] - Analysis of Slitrk1 in human brain lysate.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.65 mg/ml

SLITRK1 Antibody Summary

Immunogen
A genomic peptide made to an internal region of the human Slitrk1 protein (within residues 250-400). [Swiss-Prot Q96PX8]
Localization
Membrane; Single-pass type I membrane protein
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLITRK1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2500
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:250
Application Notes
This Slitrk1 antibody is useful for IHC and Western blot. In Western blot a band is seen ~83 kDa.
Positive Control
Brain Lysate (NB820-59177)

Reactivity Notes

Human and mouse. Immunogen sequence has 84% homology to rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS and 30% Glycerol
Preservative
0.05% Sodium Azide
Concentration
0.65 mg/ml
Purity
Immunogen affinity purified

Notes

Manufactured by Genomic Antibody Technology™. GAT FAQs

Alternate Names for SLITRK1 Antibody

  • FLJ54428
  • KIAA1910KIAA0918
  • leucine rich repeat containing 12
  • Leucine-rich repeat-containing protein 12
  • LRRC12
  • RP11-395N17.1
  • SLIT and NTRK-like family, member 1
  • SLIT and NTRK-like protein 1
  • slit and trk like gene 1
  • SLITRK1
  • TTM

Background

SLITRK1 (SLIT- and TRK-like family, member 1) is a type I transmembrane protein with an extracellular LRR (leucine-rich repeat) domain homologous to SLIT and a short intracellular domain lacking tyrosine phosphorylation motifs common among other SLITRK family members. SLITRK1 has been implicated in certain pathologies including Gilles de la Tourette syndrome (GTS) and trichotillomania (TTM). SLITRK1 has been shown to interact with 14-3-3 proteins, which are ubiquitously expressed phosphorylation-binding proteins implicated in regulation of multiple vital cellular processes such as proliferation, neuronal migration and membrane excitability. SLITRK1 has been shown to control neurite outgrowth and is expressed in embryonic as well as postembryonic brain with highest expression in cortex, thalamus and basal ganglia. SLITRK1 has also been reported to express in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

View specific protocols for SLITRK1 Antibody (NBP1-49541): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SLITRK1 Antibody (NBP1-49541) (0)

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-49541AF405
Alexa Fluor 488 Labeled NBP1-49541AF488
Alexa Fluor 647 Labeled NBP1-49541AF647
Alexa Fluor 700 Labeled NBP1-49541AF700
Biotin Labeled NBP1-49541B
DyLight 405 Labeled NBP1-49541V
DyLight 488 Labeled NBP1-49541G
DyLight 550 Labeled NBP1-49541R
DyLight 650 Labeled NBP1-49541C
FITC Labeled NBP1-49541F
HRP Labeled NBP1-49541H

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Bioinformatics

Gene Symbol SLITRK1
Entrez
Uniprot