SLC45A3/Prostein Antibody (SLC45A3/7176R)

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody (SLC45A3/7176R) [NBP3-13804] - Formalin-fixed, paraffin-embedded human prostate stained with SLC45A3/Prostein antibody (SLC45A3/7176R). Inset: PBS instead of primary antibody; secondary only negative control.

Protein Array: SLC45A3/Prostein Antibody (SLC45A3/7176R) [NBP3-13804] - Analysis of Protein Array containing more than 19,000 full-length human proteins using SLC45A3/Prostein Antibody (SLC45A3/7176R).

• Reactivity: Hu
• Applications: IHC, MA
• Clone: SLC45A3/7176R
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

SLC45A3/Prostein Antibody (SLC45A3/7176R) Summary

• Description: 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-14049)
  
  Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Synthesized peptides to the N terminus of human SLC45A3/Prostein protein (Uniprot: Q96JT2)
• Localization: Membrane
• Isotype: IgG Kappa
• Clonality: Monoclonal
• Host: Rabbit
• Gene: SLC45A3
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 1-2 ug/ml
  • Protein Array
• Application Notes: Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes
• Theoretical MW: 59 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10 mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for SLC45A3/Prostein Antibody (SLC45A3/7176R)

• IPCA-2
• IPCA-6
• IPCA-8
• PCANAP2
• PCANAP6
• PCANAP6IPCA6
• PCANAP8
• prostate cancer associated protein 2
• prostate cancer associated protein 6
• prostate cancer associated protein 8
• prostate cancer-associated gene 2
• prostate cancer-associated gene 6
• prostate cancer-associated gene 8
• Prostate cancer-associated protein 6
• Prostein
• PRST
• PRSTPCANAP2
• S45A3
• SLC45A3
• solute carrier family 45 member 3
• solute carrier family 45, member 3

Background

Prostein is a novel prostate-specific protein expressed in normal and malignant prostate tissues. This protein appears to be a type IIIa plasma membrane protein with a cleavable signal peptide and 11 transmembrane-spanning regions. Prostein expression is androgen responsive since treatment of LNCaP cells with androgen up-regulates prostein message and protein expression levels. Thus, prostein is a prostate-specific marker whose detection and quantitation may be useful in diagnosing and monitoring prostate cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC45A3
• Uniprot:
  • Q96JT2(Human)