Western Blot: SLC26A3 Antibody [NBP1-84450] - Analysis in control (vector only transfected HEK293T lysate) and SLC26A3 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T ...read more
Immunohistochemistry-Paraffin: SLC26A3 Antibody [NBP1-84450] - Analysis in human colon and skeletal muscle tissues using NBP1-84450 antibody. Corresponding SLC26A3 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: SLC26A3 Antibody [NBP1-84450] - Staining of human colon shows moderate positivity in glandular cells of apical membrane.
Immunohistochemistry-Paraffin: SLC26A3 Antibody [NBP1-84450] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: SLC26A3 Antibody [NBP1-84450] - Staining of human small intestine shows moderate to strong positivity in apical membrane in glandular cells.
This antibody was developed against Recombinant Protein corresponding to amino acids: DQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHILMKKDYSTSKFNP
Immunogen affinity purified
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Mouse reactivity reported in scientific literature (PMID: 31708126). Rat (85%).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2) and 40% Glycerol
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for SLC26A3 Antibody
chloride anion exchanger
congenital chloride diarrhea
down-regulated in adenoma protein
DRADown-regulated in adenoma
Solute carrier family 26 member 3
solute carrier family 26, member 3
SLC26A3 is encoded by this gene is a transmembrane glycoprotein that functions as a sulfate transporter. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. Mutations in this gene have been associated with congenital chloride diarrhea.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Next-Gen DNA Sequencing and SLC26A3 Research The SLC26A3, also known as DRA (downregulated-in-adenoma) gene is a member of the sulphate anion transporter family, serving an important role in the exchange and transport of chloride, bicarbonate and sulphate ions at plasma membrane sites. We at Nov... Read full blog post.
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