SLC1A5 Antibody (3085B) [Alexa Fluor® 700]

• Reactivity: Hu
• Applications: IHC, ICC/IF
• Clone: 3085B
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 700

SLC1A5 Antibody (3085B) [Alexa Fluor® 700] Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Synthetic Peptide
  Accession # Q9JKD8
• Specificity: Detects a synthetic peptide specific for human SLC1A5 around amino acid 520 in Direct ELISA.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SLC1A5 Antibody (3085B) [Alexa Fluor® 700]

• AAAT
• Alanine/serine/cysteine transporter 2
• ASC amino acid transporter-2
• ASCT2
• ATB(0)
• ATBO
• baboon M7 virus receptor
• M7V1
• M7VS1
• neutral amino acid transporter B
• neutral amino acid transporter B(0)
• R16
• RD114 virus receptor
• RD114/simian type D retrovirus receptor
• RDR
• RDRC
• SLC1A5
• Sodium-dependent neutral amino acid transporter type 2
• solute carrier family 1 (neutral amino acid transporter), member 5
• Solute carrier family 1 member 5

Background

SLC1A5 is a sodium dependent antiporter also known as ASCT2 (ASC amino acid Transporter2). It is a member of the solute carrier (SLC) superfamily of transporters and plays an important role in tumors. It is one of the 3 proteins, including SLC7A5 and SLC3A2, that are among the highest differentially expressed genes in activated lymphocytes and cancerous cells. Pharmacological inhibition of SLC1A5 was found to abrogate the effector functions of NK cells. In a pancancer analysis of SLC1A5, it has been demonstrated to be a prognostic biomarker in cancer patients.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.