HERV Antibody

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Western Blot: HERV Antibody [NB100-93579] - WB detection of HERV in human placenta lysate with NB100-93579 antibody at a dilution of 1:250

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, B/N, IHC-Fr, IHC-P, In vitro
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

HERV Antibody Summary

Immunogen
Synthetic peptide corresponding to residues 42-50 [QRPGNIDAPC] of the HERV protein.
Specificity
Human Endogenous Retroviruses (HERVs), a class of multiple-sclerosis-associated retroviruses
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ERVW-1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:250-1:1000
  • Blocking/Neutralizing
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • In vitro assay
Application Notes
This antibody is useful for Western Blot. Use in Immunohistochemistry-Paraffin reported in scientific literature (PMID 24635849). Use in In vitro, Immunohistochemistry-Frozen and blocking/neutralizing reported in scientific literature (PMID 26154387) The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
59.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reviewed Applications
Read 1 Review rated 5
using
NB100-93579 in the following applications:

Publications
Read Publications using
NB100-93579 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for HERV Antibody

  • endogenous retroviral family W, env(C7), member 1
  • ENV
  • envelope glycoprotein
  • Envelope polyprotein gPr73
  • enverin
  • ENVW
  • Env-W
  • HERV-7q Envelope protein
  • HERV7Q
  • HERV-7q
  • HERV-tryptophan envelope protein
  • HERV-W Env glycoprotein
  • HERV-W envelope protein
  • HERV-W
  • HERV-W_7q21.2 provirus ancestral Env polyprotein
  • HERV-W{7q21.1} provirus ancestral Env polyprotein
  • HERVWENV
  • HERV-W-ENV
  • HERVWenvelope protein
  • human endogenous retrovirus W envC7-1 envelope protein
  • syncytin A
  • Syncytin
  • syncytin-1

Background

HERVs are a class of multiple sclerosis associated retroviruses. Reacts with a replication competent Human Endogenous Retrovirus (HERVW) isolated from placenta. The synthetic peptide sequence used as immunogen is taken from the virus envelope polyprotein sequence. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. The HERVW endogenous envelope protein has retained its original fusogenic properties and participates in trophoblast fusion during placenta morphogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for HERV Antibody (NB100-93579)(2)

Review for HERV Antibody (NB100-93579) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Human.
We have 1 review tested in 1 application: ICC.

Reviews using NB100-93579:
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ICC
(1)
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Human
(1)
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Images Ratings Applications Species Date Details
 
reviewed by:
Greta Beckerle
ICC Human 11/15/2017
View

Summary

ApplicationImmunocytochemistry
Sample TestedBreast cancer cells
SpeciesHuman
Lot1920

Comments

CommentsTEM imaging of T47D and MCF7 breast cancer cells.

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for HERV Antibody (NB100-93579). (Showing 1 - 1 of 1 FAQs).

  1. Does the antibody recognize the HERV-W HYPER product, the digest result of the fool GENE PRODUCT HERV-W?
    • HERV Antibody [NB100-93579] is generated against immunogen sequence QRPGNIDAPC which shares sequence homology with your mentioned sequence which was..... FTLTAPPPCRCMTSSSPYQEFLWRMQRPGNIDAPSY...... Therefore, we strongly believe that our antibody NB100-93579 will be cross-reacting with your mentioned partial protein.

Secondary Antibodies

 

Isotype Controls

Additional HERV Products

Bioinformatics Tool for HERV Antibody (NB100-93579)

Discover related pathways, diseases and genes to HERV Antibody (NB100-93579). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for HERV Antibody (NB100-93579)

Discover more about diseases related to HERV Antibody (NB100-93579).

PTMs for HERV Antibody (NB100-93579)

Learn more about PTMs related to HERV Antibody (NB100-93579).

Blogs on HERV

There are no specific blogs for HERV, but you can read our latest blog posts.

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Contact Information

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Calculators

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Recent Reviews

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Greta Beckerle
11/15/2017
Application: ICC
Species: Human

Bioinformatics

Gene Symbol ERVW-1
Entrez
Uniprot