SLC1A5 Antibody (1085750) [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: WB, IHC, ICC/IF
• Clone: 1085750
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 594

SLC1A5 Antibody (1085750) [Alexa Fluor® 594] Summary

• Immunogen: Synthetic Peptide
  Accession # Q15758
• Specificity: Detects a synthetic peptide corresponding to residues near amino acid 500 of human SLC1A5 protein by Direct ELISA.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SLC1A5 Antibody (1085750) [Alexa Fluor® 594]

• AAAT
• Alanine/serine/cysteine transporter 2
• ASC amino acid transporter-2
• ASCT2
• ATB(0)
• ATBO
• baboon M7 virus receptor
• M7V1
• M7VS1
• neutral amino acid transporter B
• neutral amino acid transporter B(0)
• R16
• RD114 virus receptor
• RD114/simian type D retrovirus receptor
• RDR
• RDRC
• SLC1A5
• Sodium-dependent neutral amino acid transporter type 2
• solute carrier family 1 (neutral amino acid transporter), member 5
• Solute carrier family 1 member 5

Background

SLC1A5 is a sodium dependent antiporter also known as ASCT2 (ASC amino acid Transporter2).  It is a member of the solute carrier (SLC) superfamily of transporters and plays an important role in tumors.  It is one of the 3 proteins, including SLC7A5 and SLC3A2, that are among the highest differentially expressed genes in activated lymphocytes and cancerous cells.  Pharmacological inhibition of SLC1A5 was found to abrogate the effector functions of NK cells.  In a pancancer analysis of SLC1A5, it has been demonstrated to be a prognostic biomarker in cancer patients.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • Q15758(Human)