SH2D1A Antibody Pair [HRP]

ELISA: SH2D1A Antibody Pair [HRP] [NBP3-26916] - Standard curve reference

• Reactivity: Hu
• Applications: ELISA
• Conjugate: HRP
• Standard Curve Range: 34.38-2200 pg/mL (example only; lot dependent)
• Sensitivity: 34.38 pg/mL (example only; lot dependent)

SH2D1A Antibody Pair [HRP] Summary

• Description: Solid Phase sandwich ELISA for the quantitative determination of Human SH2D1A.
• Standard Curve Range: 34.38-2200 pg/mL (example only; lot dependent)
• Sensitivity: 34.38 pg/mL (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Sample Volume: 100 uL
• Gene: SH2D1A

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for SH2D1A Antibody Pair [HRP]

• DSHP
• DSHPLYP
• Duncan disease SH2-protein
• EBVS
• FLJ92177
• IMD5
• LYP
• MTCP1
• SAP/SH2D1A
• SAPlymphoproliferative syndrome
• SH2 domain containing 1A
• SH2 domain-containing protein 1A
• SH2D1A
• signaling lymphocyte activation molecule-associated protein
• Signaling lymphocytic activation molecule-associated protein
• SLAM associated protein/SH2 domain protein 1A
• SLAM-associated protein
• T cell signal transduction molecule SAP
• T-cell signal transduction molecule SAP
• XLP
• XLPD
• XLPDFLJ18687
• XLPSH2 domain protein 1A

Background

The cytoplasmic protein encoded by the SH2D1A gene plays an essential role in controlling EBV infection. It is expressed in T and NK cells, but not in B cells or in granulocytes. SH2D1A is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD)also known as Duncan disease. XLPD is characterized by an immunodeficiency following Epstein-Barr virus (EBV)infection. Symptoms include fatal mononucleosis, hypogammaglobulinemia, pancytopenia or malignant lymphoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: SH2D1A