Independent Antibodies: Western Blot: SFPQ Antibody [NB100-61045] - Detection of Human and Mouse SFPQ on HeLa whole cell lysate using NB100-61045. SFPQ was also immunoprecipitated by rabbit anti-SFPQ antibodies ...read more
Immunohistochemistry: SFPQ Antibody [NB100-61045] - Sample: FFPE section of human prostate carcinoma (left) and mouse CT26 colon carcinoma (right). Antibody: Affinity purified rabbit anti- PSF/SFPQ used at a dilution of ...read more
The immunogen recognized by this antibody maps to a region between residue 657 and 707 of human Polypyrimidine tract-binding protein-associated-splicing factor (Splicing factor, proline- and glutamine-rich) using the numbering given in entry NP_005057.1 (GeneID 6421).
Immunogen affinity purified
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PSF/SFPQ is a multifunctional protein know to participate in a variety of nuclear processes and may function to link transcription and pre-mRNA processing. PSF/SFPQ bears an RNA recognition motif (RRM) further indicating its role in post-transcriptional processes. PSF has been shown to associate with p54nrb/NonO to modulate androgen receptor-mediated transcription. Additionally, it has recently been show to associate with XRN2 and p54nrb/NonO to facilitate pre-mRNA 3' processing and transcription termination.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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