SF2 Antibody - BSA Free

Immunohistochemistry-Paraffin: SF2 Antibody [NBP2-38912] - Staining of human lymph node shows strong nuclear positivity in germinal and non-germinal center cells.

Immunohistochemistry-Paraffin: SF2 Antibody [NBP2-38912] - Staining of human colon shows strong nuclear positivity in glandular cells.

Immunohistochemistry-Paraffin: SF2 Antibody [NBP2-38912] - Staining of human cervix, uterine shows strong nuclear positivity in squamous epithelial cells.

Immunohistochemistry-Paraffin: SF2 Antibody [NBP2-38912] - Staining of human liver shows strong nuclear positivity in hepatocytes.

Immunohistochemistry-Paraffin: SF2 Antibody [NBP2-38912] - Staining of human rectum shows strong nuclear positivity in glandular cells.

• Reactivity: Hu, Mu, Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

SF2 Antibody - BSA Free Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to amino acids: DYDGYRLRVEFPRSGRGTGRG
• Predicted Species: Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SRSF1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  SF2 Protein (NBP2-38912PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for SF2 Antibody - BSA Free

• Alternative-splicing factor 1
• ASFpre-mRNA-splicing factor SF2, P33 subunit
• MGC5228
• serine/arginine-rich splicing factor 1
• SF2FLJ53078
• SF2p33
• SFRS1splicing factor 2
• Splicing factor, arginine/serine-rich 1ASF-1
• SR splicing factor 1
• SRp30a

Background

SF2 encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SRSF1
• Uniprot:
  • Q07955(Human)