SF2 Products

Description

SF2 encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez	6426 Human
Uniprot	AAH10264 Human NM_006924 Human NP_001071634 Human Q07955 Human NP_008855.1 Human
Product By Gene ID	6426
Alternate Names	SRp30a SF2P33 SF2p33 SR splicing factor 1 MGC5228 SFRS1splicing factor 2 SF2FLJ53078 ASFpre-mRNA-splicing factor SF2, P33 subunit Splicing factor, arginine/serine-rich 1ASF-1 Alternative-splicing factor 1 serine/arginine-rich splicing factor 1

Diseases related to SF2

Discover more about diseases related to SF2.

Malignant Neoplasms
Neoplasms
Carcinoma
Cell Transformation, Neoplastic
Malignant Neoplasm Of Breast
Tumor Angiogenesis
Pathologic Neovascularization
Malignant Neoplasm Of Lung
Adenocarcinoma
Non-small Cell Lung Carcinoma
Adenocarcinoma Of Lung (disorder)
Denys-drash Syndrome
Leukemia
Adenoma
Neoplasm Metastasis
Diabetic Nephropathy
Ataxia
Lung Diseases
Premature Aging Syndrome
Myeloid Leukemia

Pathways for SF2

View related products by pathway and learn more about each of the pathways below.

Localization
Hyperphosphorylation
Angiogenesis
Aging
Mrna Splicing
Translation
Cell Differentiation
Rna Splicing
Cellular Localization
Transport
Protein Phosphorylation
Cell Migration
Cellular Senescence
Histone Modification
Membrane Depolarization
Mrna Processing
Interphase
Cell-cell Adhesion
Response To Stress
Protein Splicing

PTMs for SF2

Learn more about PTMs related to SF2.

Phosphorylation
Methylation
Oxidation

Bioinformatics Tool for SF2

Discover related pathways, diseases and genes to SF2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.