SF-1/NR5A1/Steroidogenic Factor 1 Antibody

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Immunohistochemistry-Paraffin: SF-1/NR5A1/Steroidogenic Factor 1 Antibody [NBP1-02349] - Staining of human testis.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bt, Bv, Ca, Ha, Mk, Op, Pm, RbSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.7 mg/ml

Order Details

SF-1/NR5A1/Steroidogenic Factor 1 Antibody Summary

Immunogen
Synthetic 17 amino acid peptide from near C-terminus of human NR5A1.
Specificity
Human NR5A1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Mouse (94%), Rat (94%), Hamster (94%), Canine (94%), Bat (94%), Primate (94%), Monkey (94%), Opossum (94%), Bovine (94%), Rabbit (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NR5A1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 18 ug/ml.
  • Immunohistochemistry-Paraffin 18 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (94%), Gibbon (94%), Marmoset (94%), Elephant (94%), Panda (88%), Equine (88%), Porcine (88%), Turkey (88%), Chicken (88%), Platypus (82%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
0.7 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SF-1/NR5A1/Steroidogenic Factor 1 Antibody

  • AD4BP
  • AD4BPSTF-1
  • Adrenal 4-binding protein
  • ELP
  • FTZ1adrenal 4 binding protein
  • FTZF1
  • FTZF1nuclear receptor AdBP4
  • Fushi tarazu factor homolog 1
  • NR5A1
  • Nuclear receptor subfamily 5 group A member 1
  • nuclear receptor subfamily 5, group A, member 1
  • SF1
  • SF-1
  • SF-1POF7
  • SF1steroidogenic factor 1
  • Steroid hormone receptor Ad4BP
  • steroidogenic factor-1

Background

Steroidogenic factor 1 (SF-1), a NR5 Fushi Tarazu-Like Receptor, has been shown to affect sexual differentiation, steroid metabolism, and neural development. SF-1 binds as a monomer and regulates all steroidogenic p450 genes, Mullerian inhibiting substance, the gonadotrophins, the ACTH receptor, oxytocin, nuclear receptor DAX-1, and several other genes. Four alternatively spliced isoforms of SF-1 have been isolated in mice, and they differ at the N and C termini but are identical in the DNA-binding domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NR5A1
Entrez
Uniprot