SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free

Immunohistochemistry-Paraffin: SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free [NBP1-02349] - Staining of human testis.

Product Discontinued

SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 17 aa peptide from near C-terminus of human SF-1/NR5A1/Steroidogenic Factor 1.
• Epitope: C-Terminus
• Specificity: Human NR5A1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Mouse (94%), Rat (94%), Hamster (94%), Canine (94%), Bat (94%), Primate (94%), Monkey (94%), Bovine (94%), Rabbit (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NR5A1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 2.5 - 5 ug/ml
  • Immunohistochemistry-Paraffin 2.5-5 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (94%), Gibbon (94%), Marmoset (94%), Elephant (94%), Panda (88%), Equine (88%), Porcine (88%), Turkey (88%), Chicken (88%), Platypus (82%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 0.7 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free

• AD4BP
• AD4BPSTF-1
• Adrenal 4-binding protein
• ELP
• FTZ1adrenal 4 binding protein
• FTZF1
• FTZF1nuclear receptor AdBP4
• Fushi tarazu factor homolog 1
• NR5A1
• Nuclear receptor subfamily 5 group A member 1
• nuclear receptor subfamily 5, group A, member 1
• SF1
• SF-1
• SF-1POF7
• SF1steroidogenic factor 1
• Steroid hormone receptor Ad4BP
• steroidogenic factor-1

Background

Steroidogenic factor 1 (SF-1), a NR5 Fushi Tarazu-Like Receptor, has been shown to affect sexual differentiation, steroid metabolism, and neural development. SF-1 binds as a monomer and regulates all steroidogenic p450 genes, Mullerian inhibiting substance, the gonadotrophins, the ACTH receptor, oxytocin, nuclear receptor DAX-1, and several other genes. Four alternatively spliced isoforms of SF-1 have been isolated in mice, and they differ at the N and C termini but are identical in the DNA-binding domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NR5A1
• Entrez:
  • 2516(Human)
• Uniprot:
  • Q13285()