SF-1/NR5A1/Steroidogenic Factor 1 Antibody (N1665) [Unconjugated]

• Reactivity: Hu
• Applications: WB, IHC, IP
• Clone: N1665
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

SF-1/NR5A1/Steroidogenic Factor 1 Antibody (N1665) [Unconjugated] Summary

• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SF-1/NR5A1/Steroidogenic Factor 1 Antibody (N1665) [Unconjugated]

• AD4BP
• AD4BPSTF-1
• Adrenal 4-binding protein
• ELP
• FTZ1adrenal 4 binding protein
• FTZF1
• FTZF1nuclear receptor AdBP4
• Fushi tarazu factor homolog 1
• NR5A1
• Nuclear receptor subfamily 5 group A member 1
• nuclear receptor subfamily 5, group A, member 1
• SF1
• SF-1
• SF-1POF7
• SF1steroidogenic factor 1
• Steroid hormone receptor Ad4BP
• steroidogenic factor-1

Background

Streroidogenic Factor 1 (SF-1, AD4BP, FTZ-F1; NR5A1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development, including the hypothalamic-pituitary-gonadal axis and sex determination.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SF-1/NR5A1/Steroidogenic Factor 1 Antibody (PP-N1665-0C)(2)

Publications using PP-N1665-0C

• B Lu, Y Xia, J Chen, J Tang, Y Shao, W Yu NCOA1/2/3 rearrangements in uterine tumor resembling ovarian sex cord tumor: a clinicopathological and molecular study of 18 cases Human pathology, 2023-01-13;0(0):. 2023-01-13 [PMID: 36646185] (IHC, Human)
• K Kaneko, HY Lin, Y Fu, PK Saha, AB De la Puen, Y Xu, K Ohinata, P Chen, A Morozov, M Fukuda Rap1 in the VMH regulates glucose homeostasis JCI Insight, 2021-06-08;0(0):. 2021-06-08 [PMID: 33974562] (IHC, Mouse)