SF-1/NR5A1/Steroidogenic Factor 1 Antibody (1036706) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: IHC, ICC/IF
• Clone: 1036706
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

SF-1/NR5A1/Steroidogenic Factor 1 Antibody (1036706) [Alexa Fluor® 488] Summary

• Immunogen: Human SF‑1/NR5A1 synthetic peptide
  Accession # Q13285
• Specificity: Detects human SF‑1/NR5A1 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SF-1/NR5A1/Steroidogenic Factor 1 Antibody (1036706) [Alexa Fluor® 488]

• AD4BP
• AD4BPSTF-1
• Adrenal 4-binding protein
• ELP
• FTZ1adrenal 4 binding protein
• FTZF1
• FTZF1nuclear receptor AdBP4
• Fushi tarazu factor homolog 1
• NR5A1
• Nuclear receptor subfamily 5 group A member 1
• nuclear receptor subfamily 5, group A, member 1
• SF1
• SF-1
• SF-1POF7
• SF1steroidogenic factor 1
• Steroid hormone receptor Ad4BP
• steroidogenic factor-1

Background

NR5A1 (STF1) is a transcriptional activator essential for sexual differentiation and formation of the primary steroidogenic tissues.  Mutations in the NR5A1 gene result in multiple diseases ranging from infertility (SFPG8), premature ovarian failure (POF7), adrenal insufficiency (AINR), female to male sex reversal (SRXX4) and male to female sex reversal (SRXY3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.