SETD7/9 Products


Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly(ADP-ribosylation), ubiquitination and methylation. These modifications play critical roles in regulating chromatin structure and gene expression. Histone methyltransferases (HMTases) selectively methylate evolutionarily conserved arginine or lysine residues, primarily in the N-terminal tails of histones H3 and H4. Set7/9 is a histone specific HMTase that methylates histone H3 lysine 4. Set7/9 transfers methyl groups to lysine 4 of histone H3 in complex with S-adenosyl-L-methionine. Human Set7/9 is a 336 amino acid protein.


Entrez Mouse
Uniprot Human
Product By Gene ID 80854
Alternate Names
  • EC
  • SET9
  • histone-lysine N-methyltransferase SETD7
  • Lysine N-methyltransferase 7
  • histone H3-lysine 4-specific methyltransferase
  • SET7/9Histone H3-K4 methyltransferase SETD7
  • KMT7FLJ21193
  • SET7Set9
  • KIAA1717SET domain-containing protein 7
  • H3-K4-HMTase SETD7
  • SET domain containing (lysine methyltransferase) 7

PTMs for SETD7/9

Learn more about PTMs related to SETD7/9.


Bioinformatics Tool for SETD7/9

Discover related pathways, diseases and genes to SETD7/9. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.