Serpin F1/PEDF Antibody (187003) [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 187003
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

Serpin F1/PEDF Antibody (187003) [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant human Serpin F1, Mouse myeloma cell line NS0-derived recombinant human Serpin F1, and S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Serpin F1
  Asp44-Pro418
  Accession # P36955
• Specificity: Detects human Serpin F1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse Serpin F1 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Serpin F1/PEDF Antibody (187003) [Alexa Fluor® 405]

• Cell proliferation-inducing gene 35 protein
• EPC-1
• EPC-1PIG35
• PEDF
• PEDFpigment epithelium-derived factor
• pigment epithelium derived factor), member 1
• proliferation-inducing protein 35
• serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin
• Serpin F1
• serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epitheliumderived factor), member 1

Background

Serpin F1, also known as pigment epithelium derived factor (PEDF), is a secreted glycoprotein that shows sequence and structural similarity with the serpin superfamily proteins, but lacks serine protease inhibitory activity. Serpin F1 has been shown to have cell-type specific functions including inhibition of retinal angiogenesis and neurotrophic activity in the retina and central nervous system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.