Semaphorin 6A Antibody (201932) [Alexa Fluor® 647]

• Reactivity: Mu
• Applications: WB, IHC
• Clone: 201932
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 647

Semaphorin 6A Antibody (201932) [Alexa Fluor® 647] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Semaphorin 6A
  Gly19-Thr649
  Accession # O35464
• Specificity: Detects mouse Semaphorin 6A in direct ELISAs and Western blots. In direct ELISAs, approximately 40% cross-reactivity with recombinant human (rh) Semaphorin 6A is observed and no cross-reactivity with recombinant mouse Semaphorins 3C, 3
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Semaphorin 6A Antibody (201932) [Alexa Fluor® 647]

• KIAA1368HT018
• sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
• Sema VIA
• SEMA
• Sema6A
• SEMA6A1
• SEMA6A-1
• Semaphorin 6A
• semaphorin 6A-1
• Semaphorin VIA
• semaphorin-6A
• Semaphorin-6A-1
• SEMAQ
• VIA

Background

Semaphorin 6A (Sema6A) is a member of the class 6 semaphorin family of type I transmembrane proteins important in axon guidance during neuronal development. Class 6 semaphorins mediate bidirectional signaling, in part through interaction with plexin A1. In addition to neuronal expression, Semaphorin 6A is induced by IFN-gamma in Langerhans cells. Mature mouse and human Semaphorin 6A extracellular domains share 95% amino acid sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.