SC35 Antibody [Janelia Fluor® 669]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 669

SC35 Antibody [Janelia Fluor® 669] Summary

• Immunogen: splicing factor, arginine/serine-rich 2. (Uniprot# Q01130)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SRSF2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SC35 Antibody [Janelia Fluor® 669]

• PR264
• SC35
• SC-35
• serine/arginine-rich splicing factor 2
• SFRS2
• SFRS2A
• splicing component, 35 kDa
• splicing factor SC35
• splicing factor, arginine/serine-rich 2
• SR splicing factor 2
• SRp30b

Background

SC35 is involved in pre-mRNA splicing and is found in the bodies in the nucleus referred to as speckles, SC 35 domains or splicing factor compartments (SFCs). The SC-35 clone is frequently used as a marker for these bodies, the role of which is controversial. Speckles correspond largely if not entirely to ultrastructures termed interchromatin granule clusters (IGCs). SC35 is excluded from the nucleolus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SRSF2