RPSA Antibody (MLuC5)

Images

 
Western Blot: RPSA Antibody (MLuC5) [NB200-631] - Analysis of 25 ug of HepG2 (lane 1) and Hela (lane 2) cell lysates.
Immunocytochemistry/ Immunofluorescence: RPSA Antibody (MLuC5) [NB200-631] - Analysis of Laminin Receptor (green) showing staining in the membrane of MCF-7 cells (right) compared to a negative control without primary ...read more
Immunohistochemistry-Paraffin: RPSA Antibody (MLuC5) [NB200-631] - Human breast carcinoma stained with Laminin Receptor antibody using peroxidase-conjugate and DAB chromogen. Note cell membrane with some cytoplasmic ...read more
Flow Cytometry: RPSA Antibody (MLuC5) [NB200-631] - Analysis of Laminin Receptor in MCF-7 cells (green) compared to an isotype control (blue).

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-P
Clone
MLuC5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

RPSA Antibody (MLuC5) Summary

Immunogen
Small cell lung carcinoma N592 live cells
Localization
Cell membrane with some cytoplasmic.
Isotype
IgM
Clonality
Monoclonal
Host
Mouse
Gene
RPSA
Purity
Ammonium sulfate precipitation
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:10 - 1:200
  • Flow Cytometry 1:10 - 1:1000
  • Immunocytochemistry/Immunofluorescence 1:10 - 1:200
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Paraffin 4 - 8 ug/mL

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 21320497).

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4) and 0.2% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Ammonium sulfate precipitation

Alternate Names for RPSA Antibody (MLuC5)

  • 37 kDa laminin receptor precursor
  • 37/67 kDa laminin receptor
  • 37LRPNEM/1CHD4
  • 67 kDa laminin receptor
  • 67kD, ribosomal protein SA
  • 67LR
  • Colon carcinoma laminin-binding protein
  • LAMBR37 kDa laminin receptor
  • laminin binding protein
  • laminin receptor 1 (67kD, ribosomal protein SA)
  • Laminin receptor 1
  • Laminin-binding protein precursor p40
  • LAMR 1
  • lamR
  • LAMR140S ribosomal protein SA
  • LBP
  • LBP/p40
  • LRP
  • LRP/LR
  • Multidrug resistance-associated protein MGr1-Ag
  • p40
  • ribosomal protein SA

Background

Laminin, one of the major glycoproteins of basement membrane, displays multiple biological activities which are mediated through its interaction with specific cell membrane receptors. Overexpression of laminin receptor is reportedly an independent prognostic factor in breast cancer and correlates with the dissemination of the tumor cells in bone marrow. Laminin receptor appears to play an important role in tumor invasion and metastasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol RPSA
Entrez
Uniprot