RP105/CD180 Antibody

Western Blot: RP105/CD180 Antibody [NBP1-40277] - Analysis of anti-CD180 / RP105 antibody with human spleen tissue lysate at (A) 0.5 and (B) 1 ug/ml.

Immunocytochemistry/Immunofluorescence: RP105/CD180 Antibody [NBP1-40277] - Immunofluorescence of RP105/CD180 in human spleen tissue with RP105/CD180 antibody at 20 ug/ml.

Immunohistochemistry-Paraffin: RP105/CD180 Antibody [NBP1-40277] - Analysis of anti-CD180 / RP105 antibody with human colon at concentration 5 ug/ml.

Immunohistochemistry-Paraffin: RP105/CD180 Antibody [NBP1-40277] - Analysis of anti-CD180 / RP105 antibody with human tonsil at concentration 5 ug/ml.

Product Discontinued

RP105/CD180 Antibody Summary

• Immunogen: An 11 aa synthetic peptide near the N-terminus of human RP105/CD180. The immunogen is located within the first 50 aa of RP105/CD180.
• Epitope: N-Terminus
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CD180
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 0.5-1 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for RP105/CD180 Antibody

• CD180 antigenMGC126233
• CD180 molecule
• CD180
• Ly64
• LY64MGC126234
• Ly78
• Lymphocyte antigen 64
• lymphocyte antigen-64, radioprotective, 105kDa
• Radioprotective 105 kDa protein
• RP105
• RP105lymphocyte antigen 64 (mouse) homolog, radioprotective, 105kD

Background

RP105 (CD180) is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD1 and form the cell surface receptor complex, RP105/MD1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD180
• Entrez:
  • 4064(Human)
• Uniprot:
  • Q99467(Human)