MD-1/LY86 Antibody

Images

 
Western Blot: MD-1/LY86 Antibody [NB100-56700] - Analysis of MD-1 in Ramos lysate using MD-1 antibody at 2 ug/ml.
Immunohistochemistry-Paraffin: MD-1/LY86 Antibody [NB100-56700] - Analysis of human spleen using MD-1 antibody at 10 ug/ml.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

MD-1/LY86 Antibody Summary

Immunogen
This antibody was developed against a KLH-conjugated synthetic peptide corresponding to amino acids 112-125 of human MD-1.
Specificity
In Ramos, a 25 kDa band is observed.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LY86
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 2 ug/ml
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Publications
Read Publications using
NB100-56700 in the following applications:

  • WB
    1 publication

Reactivity Notes

Cross reacts with Human and Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein G purified

Alternate Names for MD-1/LY86 Antibody

  • LY86
  • Ly-86
  • lymphocyte antigen 86
  • MD1
  • MD-1
  • MMD-1
  • Protein MD-1
  • RP105-associated

Background

Mammalian MD-1 is a homolog of Chicken MD-1, which was previously isolated as a v-myb-regulated gene, since its transcription increases rapidly after v-myb induction. MD-1 is associated at the cell surface with RP105. RP105 is a leucine-rich repaeat (LRR) molecule that is expressed on B-lymphocytes. It was first identified by a mAb that protects spleen B cells from irradiation-induced apoptosis (2). LRR proteins, such as Toll receptors, have a role in innate immunity. MD-1 does not have any homology to other molecules. MD-1 when expressed alone behaves as a secretory protein. Expression of MD-1 in a cell increases the expression of RP105.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MD-1/LY86 Antibody (NB100-56700)(3)

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Bioinformatics

Gene Symbol LY86
Entrez
Uniprot