RIN1 Antibody - BSA Free

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

RIN1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit RIN1 Antibody - BSA Free (NBP3-30812) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: His-tagged recombinant human RIN1 protein
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RIN1
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody detects recombinant Rin protein expressed in HEK-293 cells by Western blot analysis. Shows minimal cross-reactivity with Rit protein and other Ras proteins..

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Phosphate buffered saline
• Preservative: 0.08% Sodium Azide
• Purity: Ammonium sulfate precipitation

Alternate Names for RIN1 Antibody - BSA Free

• Ras and Rab interactor 1
• ras inhibitor 1
• Ras inhibitor JC99
• ras inhibitor RIN1
• Ras interaction/interference protein 1

Background

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RIN1