Reg3A Antibody

• Reactivity: Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

Reg3A Antibody Summary

• Immunogen: E. coli-derived recombinant rat Reg3A
  Glu26-Gln174
  Accession # NP_742074
• Specificity: Detects rat Reg3A in direct ELISAs and Western blots. In Western blots, approximately 30% cross‑reactivity with recombinant mouse (rm) Reg3A is observed and less than 5% cross-reactivity with rmReg1, recombinant human (rh) Reg1B, recombinant rat Reg2 and rhReg4 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: REG3A
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Reg3A Antibody

• hepatocarcinoma-intestine-pancreas
• HIPpancreatitis-associated protein
• Human proislet peptide
• Lithostathine 3
• pancreatic beta cell growth factor
• Pancreatitis-associated protein 1
• PAP homologous protein
• PAP1FLJ18565
• PAP2
• PAPPAP-H
• PBCGF
• proliferation-inducing protein 34
• proliferation-inducing protein 42
• Reg III-alpha
• REG3
• Reg3A
• REG-3-alpha
• regenerating islet-derived 3 alpha
• regenerating islet-derived protein 3-alpha
• Regenerating islet-derived protein III-alpha
• REG-III

Background

Rat Reg3A, also named lithostathine 3 and pancreatitis-associated protein 2, belongs to the Regenerating gene family (Reg), within the superfamily of C-type lectins. Rat Reg3A is overexpressed during the acute phase of pancreatitis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Reg3A Antibody (AF1745)(3)

Publications using AF1745

• Richard Coffey, Hyeyoung Nam, Mitchell D. Knutson Microarray Analysis of Rat Pancreas Reveals Altered Expression of Alox15 and Regenerating Islet-Derived Genes in Response to Iron Deficiency and Overload PLoS ONE 2014-01-21 [PMID: 24465846]
• Vanessa Fétaud-Lapierre, Catherine M. Pastor, Manuel Jorge-Costa, Denis F. Hochstrasser, Denis R. Morel, Jean-Louis Frossard et al. Time-course proteomic analysis of taurocholate-induced necrotizing acute pancreatitis Journal of Proteomics 2013-06-24 [PMID: 23624238]
• Vanessa Fétaud-Lapierre, Catherine M. Pastor, Annarita Farina, Denis F. Hochstrasser, Jean-Louis Frossard, Pierre Lescuyer Proteomic Analysis of Heat Shock-Induced Protection in Acute Pancreatitis Journal of Proteome Research 2010-11-05 [PMID: 20815342]

Bioinformatics

• Gene Symbol: REG3A
• Uniprot:
  • NP_742074()