RASGRP3 Antibody

Images

 
Western Blot: RASGRP3 Antibody [H00025780-D01P] - Analysis of RASGRP3 expression in mouse kidney.
Immunocytochemistry/ Immunofluorescence: RASGRP3 Antibody [H00025780-D01P] - Analysis of antibody to RASGRP3 on HeLa cell. Antibody concentration 30 ug/ml.
Western Blot: RASGRP3 Antibody [H00025780-D01P] - Analysis of RASGRP3 expression in transfected 293T cell line by RASGRP3 polyclonal antibody.Lane 1: RASGRP3 transfected lysate(78.30 KDa).Lane 2: Non-transfected lysate.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

RASGRP3 Antibody Summary

Immunogen
RASGRP3 (NP_733772.1, 1 a.a. ~ 690 a.a) full-length human protein.MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYRNATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDISSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGLSHSSISR
Specificity
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RASGRP3
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
This antibody is reactive against mammalian transfected lysate in western blot. May also be used for ELISA.

Reactivity Notes

Human, Mouse

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for RASGRP3 Antibody

  • Calcium and DAG-regulated guanine nucleotide exchange factor III
  • GRP3KIAA0846ras guanyl-releasing protein 3
  • Guanine nucleotide exchange factor for Rap1
  • RAS guanyl releasing protein 3 (calcium and DAG-regulated)

Background

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol RASGRP3
Entrez
Uniprot