Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse monoclonal
Species: Hu, Mu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
25780 |
| Alternate Names |
- Calcium and DAG-regulated guanine nucleotide exchange factor III
- GRP3KIAA0846ras guanyl-releasing protein 3
- Guanine nucleotide exchange factor for Rap1
- RAS guanyl releasing protein 3 (calcium and DAG-regulated)
|
Research Areas for RASGRP3
Find related products by research area and learn more about each of the different research areas below.
Phospho-Specific
