Quantikine Immunoassay Control Group 244 for Human IL-33 Summary
Additional Information |
For use with catalog number D3300B |
Source |
N/A |
Inter-Assay |
See PDF Datasheet for details |
Intra-Assay |
See PDF Datasheet for details |
Spike Recovery |
See PDF Datasheet for details |
Sample Volume |
See PDF Datasheet for details |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Quantikine Immunoassay Control Group 244 for Human IL-33
Background
IL-33 (Interleukin-33) is released from physically damaged or necrotic cells. It triggers Th2-biased immune cell activation at sites of inflammation as well as regulatory T cell and M2 macrophage expansion. It additionally induces angiogenesis, promotes tumor cell migration and invasion, limits cardiac myocyte hypertrophy, and limits the development of atherosclerotic plaques. IL-33 signals through a receptor complex composed of ST2 and IL-1 RAcP. IL-1 RAcP also associates with IL-1 RI, IL-1 RII, IL-1 R6, and SCF R/c-kit. Soluble isoforms of ST2 and IL-1 RAcP function as decoy receptors that regulate IL-33 bioactivity.
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