IL-33 Products

Antibodies
IL-33 Antibody (40015D) [Unco ...
IL-33 Antibody (40015D) [Unconjuga...
MAB36254
Species: Hu
Applications: WB, IHC, Neut
Host: Goat Monoclonal
IL-33 Antibody (40015C) [Unco ...
IL-33 Antibody (40015C) [Unconjuga...
MAB36253
Species: Hu
Applications: WB, IHC, ELISA(Cap)
Host: Goat Monoclonal
IL-33 Antibody (1061A) [Uncon ...
IL-33 Antibody (1061A) [Unconjugated]
MAB36252
Species: Hu
Applications: IHC
Host: Rabbit Monoclonal
ELISA Kits
IL-33 ELISA Kit
IL-33 ELISA Kit
NBP2-31048
Species: Hu
Applications: ELISA
IL-33 ELISA Kit
IL-33 ELISA Kit
NBP1-84818
Lysates
IL-33 Overexpression Lysate ( ...
IL-33 Overexpression Lysate (Native)
NBL1-11954
Applications: WB
IL-33 Overexpression Lysate ( ...
IL-33 Overexpression Lysate (Denat...
H00090865-T01
Species: Hu
Applications: WB
Proteins
Rat IL-33 Protein
Rat IL-33 Protein
NBP2-35248
Species: Rt
Applications: Func, PAGE
Mouse IL-33 Protein
Mouse IL-33 Protein
NBP2-35124
Species: Mu
Applications: Func, PAGE
Human IL-33 Protein
Human IL-33 Protein
NBP2-34871
Species: Hu
Applications: Func, PAGE

Description

Interleukin 33 (IL-33) is a 32kDa proinflammatory cytokine and intracellular nuclear factor with transcriptional regulatory properties. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 90865
Alternate Names
  • NFHEV
  • IL-1F11
  • IL1F11
  • Nuclear factor from high endothelial venules
  • interleukin-33
  • Interleukin-1 family member 11
  • DVS27-related protein
  • DVS27
  • RP11-575C20.2
  • DKFZp586H0523
  • C9orf26chromosome 9 open reading frame 26 (NF-HEV)
  • NF-HEVNFEHEV
  • IL-33
  • interleukin 33

PTMs for IL-33

Learn more about PTMs related to IL-33.

Cleavage
Phosphorylation
Methylation
Biotinylation
Reduction
Citrullination

Bioinformatics Tool for IL-33

Discover related pathways, diseases and genes to IL-33. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related IL-33 Blog Posts

Check out the latest blog posts on IL-33.
Interleukin 33 (IL-33) - A dual function cytokine
IL-33 is a member of the interleukin family of cytokines that regulates a wide variety of cellular functions. Its receptor is ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and the IL-1R accessory...    Read more.
Read more IL-33 related blogs.