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IL-33 Products

Antibodies
IL-33 Antibody [Unconjugated] ...
IL-33 Antibody [Unconjugated]
AF3626
HAF109). A specific band was detected for IL-33 at approximately 37 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot IL-33 Antibody [Unconjugated]
CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in lymphocytes. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry IL-33 Antibody [Unconjugated]
NL001) and counterstained with DAPI (blue, lower panel). View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry IL-33 Antibody [Unconjugated]
AB-108-C, open histogram) followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules." class="big_lightbox" target="_blank"> Flow Cytometry IL-33 Antibody [Unconjugated]
AB-108-C, open histogram), followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin." class="big_lightbox" target="_blank"> Intracellular Staining by Flow Cytometry IL-33 Antibody [Unconjugated]
3626-ML) stimulates proliferation in the D10.G4.1 mouse helper T cell line in a dose-dependent manner (orange line), as measured by Resazurin (Catalog # AR002). Proliferation elicited by Recombinant Mouse IL-33 (0.25 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse IL-33 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3626). The ND50 is typically 10-50 ng/mL." class="big_lightbox" target="_blank"> Neutralization IL-33 Antibody [Unconjugated]
3626-ML) was serially diluted and captured by Goat Anti-Mouse IL‑33 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3626) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Mouse IL‑33 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3626) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank"> ELISA IL-33 Antibody [Unconjugated]
3626-ML) was serially diluted and captured by Goat Anti-Mouse IL‑33 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3626) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Mouse IL‑33 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3626) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank"> ELISA IL-33 Antibody [Unconjugated]
Species: Mu
Applications: WB, IHC, B/N, CyTOF-ready, ELISA(Cap), Flow, ICC/IF
Host: Goat Polyclonal
IL-33 Antibody [Unconjugated] ...
IL-33 Antibody [Unconjugated]
AF3625
3625-IL) stimulates proliferation in the D10.G4.1 mouse helper T cell line in a dose-dependent manner (orange line). Under these conditions, proliferation elicited by Recombinant Human IL-33 (1 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human IL-33 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3625). The ND50 is typically ≤ 3.0 µg/mL." class="big_lightbox" target="_blank"> Neutralization IL-33 Antibody [Unconjugated]
CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to nuclei. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry IL-33 Antibody [Unconjugated]
VC004) and DAB chromogen (lower image, yellow-brown). Tissues were counterstained with hematoxylin (blue)." class="big_lightbox" target="_blank"> Dual RNAscope ISH-IHC Compatible IL-33 Antibody [Unconjugated]
Species: Hu
Applications: WB, IHC, B/N, Dual ISH-IHC, ELISA(Cap), ICC/IF
Host: Goat Polyclonal
IL-33 Antibody (396118) [Unco ...
IL-33 Antibody (396118) [Unconjuga...
MAB3626
HAF005). Specific bands were detected for IL-33 at approximately 18 and 35 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot IL-33 Antibody (396118) [Unconjugated]
NL013) and counterstained with DAPI (blue, lower panel). View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry IL-33 Antibody (396118) [Unconjugated]
MAB006, open histogram), followed by Phycoerythrin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0105B). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules." class="big_lightbox" target="_blank"> Intracellular Staining by Flow Cytometry IL-33 Antibody (396118) [Unconjugated]
Species: Mu
Applications: WB, CyTOF-ready, Flow, ICC/IF
Host: Rat Monoclonal
Antibody Pairs
IL-33 Antibody Pair [HRP]
IL-33 Antibody Pair [HRP]
NBP2-79592
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
Mouse IL-33 DuoSet ELISA, 15 ...
Mouse IL-33 DuoSet ELISA, 15 Plate
DY3626
Species: Mu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Mouse/Rat IL-33 Quantikine EL ...
Mouse/Rat IL-33 Quantikine ELISA Kit
M3300
Species: Mu, Rt
Applications: ELISA
Quantikine Immunoassay Contro ...
Quantikine Immunoassay Control Gro...
QC244
Species: Hu
Applications: Ctrl
Lysates
IL-33 Overexpression Lysate
IL-33 Overexpression Lysate
NBL1-11954
Species: Hu
Applications: WB
Proteins
Recombinant Mouse IL-33 Prote ...
Recombinant Mouse IL-33 Protein
3626-ML
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human IL-33 Prote ...
Recombinant Human IL-33 Protein
3625-IL
Species: Hu
Applications: Bioactivity
Recombinant Human IL-33 Bioti ...
Recombinant Human IL-33 Biotinylat...
BT3625
523-ST) is immobilized at 0.5 µg/mL (100 µL/well), Biotinylated Recombinant Human IL‑33 Protein (Catalog # BT3625) binds with an ED50 of 0.900-9.00 ng/mL." class="big_lightbox" target="_blank"> Binding Activity IL-33 [Biotin]
Species: Hu
Applications: Bioactivity
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  

Description

Interleukin 33 (IL-33) is a 32kDa proinflammatory cytokine and intracellular nuclear factor with transcriptional regulatory properties. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1.

Bioinformatics

Entrez Rat
Mouse
Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 90865
Alternate Names
  • C9orf26chromosome 9 open reading frame 26 (NF-HEV)
  • DKFZp586H0523
  • DVS27
  • DVS27-related protein
  • IL1F11
  • IL-1F11
  • IL-33
  • interleukin 33
  • Interleukin-1 family member 11
  • interleukin-33
  • NFHEV
  • NF-HEVNFEHEV
  • Nuclear factor from high endothelial venules
  • RP11-575C20.2

Related IL-33 Blog Posts

Check out the latest blog posts on IL-33.
Interleukin 33 (IL-33) - A dual function cytokine
IL-33 is a member of the interleukin family of cytokines that regulates a wide variety of cellular functions. Its receptor is ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and the IL-1R accessory ...    Read more.
Read more IL-33 related blogs.