PTS [p Ser19] Antibody (24GB800)

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, ICC/IF
• Clone: 24GB800
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

PTS [p Ser19] Antibody (24GB800) Summary

• Immunogen: A synthesized peptide derived from human Phospho-PTS (S19) (Uniprot: Q03393)
• Modification: p Ser19
• Specificity: This antibody detects endogenous levels of PTS only when phosphorylated at S19
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: PTS
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for PTS [p Ser19] Antibody (24GB800)

• 6-pyruvoyl tetrahydrobiopterin synthase
• 6-pyruvoyltetrahydropterin synthase
• EC 4.2.3.12
• FLJ97081
• PTPSPTP synthase

Background

The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTS