PTS Products

Description

The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Product By Gene ID	5805
Alternate Names	6-pyruvoyl tetrahydrobiopterin synthase 6-pyruvoyltetrahydropterin synthase EC 4.2.3.12 FLJ97081 PTPSPTP synthase

Research Areas for PTS

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific