Species: Hu, Mu, RM
Applications: WB, ICC/IF, IHC, KO
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
5805 |
| Alternate Names |
- 6-pyruvoyl tetrahydrobiopterin synthase
- 6-pyruvoyltetrahydropterin synthase
- EC 4.2.3.12
- FLJ97081
- PTPSPTP synthase
|
Research Areas for PTS
Find related products by research area and learn more about each of the different research areas below.
Phospho-Specific
![Western Blot PTS [p Ser19] Antibody (SR1297) - BSA Free](http://images.novusbio.com/fullsize/nbp3-21604_rabbit-pts-p-ser-19-mab-sr1297-57202317215179.jpg)
