PTEN Peptide

Product Discontinued

PTEN Peptide Summary

• Description: A peptide to PTEN.
• Specificity: This peptide is specific for NB100-1474 only.
• Protein/Peptide Type: Peptide
• Gene: PTEN

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NB100-1474.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Preservative: No Preservative

Alternate Names for PTEN Peptide

• BZS
• EC 3.1.3.16,10q23del
• EC 3.1.3.48
• EC 3.1.3.67
• GLM2
• MMAC1 phosphatase and tensin homolog deleted on chromosome 10
• MMAC1
• MMAC1MGC11227
• Mutated in multiple advanced cancers 1
• phosphatase and tensin homologDEC
• phosphatidylinositol-34,5-trisphosphate 3-phosphatase and dual-specificityprotein phosphatase PTEN
• PTEN
• PTEN1
• TEP1MHAM

Background

PTEN is a protein tyrosine phosphatase that acts as a tumor suppressor, as a lipid phosphatase that dephosphorylates the D3 position of phosphatidylinositol 3,4,5-trisphosphate and as an antagonist of the PI3k/AKT signaling pathway (1-3). PTEN structural domains includes an N-terminal phosphatase domain, a lipid binding C2 domain and a 50-amino acid C-terminal tail that contains a PD biding sequence (5). Phosporylation of the tail of the protein will suppress its activity and modify its conformation to a

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTEN