PTBP2 Antibody

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

PTBP2 Antibody Summary

Immunogen
Peptide with sequence C-SKKFKGEDKMD corresponding to internal region according to NP_067013.1.
Epitope
SKKFKGEDKMD
Localization
Nuclear
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
PTBP2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:1000
Application Notes
WB: Preliminary experiments gave an approx. 35 kDa band in lysates of NIH3T3 after 0.1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 57.5 kDa band according to NP_067013.1. The 35 kDa band was successfully blocked by incubation with the immunizing peptide.
Positive Control
PTBP2 Lysate (NBL1-14920)
Publications
Read Publication using NB100-77333.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for PTBP2 Antibody

  • brPTB
  • FLJ34897
  • neural polypyrimidine tract binding protein
  • Neural polypyrimidine tract-binding protein
  • Neurally-enriched homolog of PTB
  • nPTB
  • nPTB6
  • nPTB7
  • nPTB8
  • polypyrimidine tract binding protein 2
  • polypyrimidine tract-binding protein 2
  • PTB-like protein
  • PTBPTBLPnPTB5
  • splicing regulator

Background

PTPBP2 is an RNA-binding protein which binds to intronic polypyrimidine tracts. It binds to the CUCUCU splicing repressor element of the downstream control sequence (DCS) and mediates negative regulation of exons splicing. It may also have a role in the regulation of translation. PTBP2 is thought to be involved in the switch to neuronal specific alternative splicing patterns during neuronal differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PTBP2 Antibody (NB100-77333)(1)

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FAQs for PTBP2 Antibody (NB100-77333) (0)

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PTBP2
Entrez
Uniprot