PSAP Antibody

Product Discontinued

PSAP Antibody Summary

• Immunogen: Prostatic acid phosphatase isolated from human seminal plasma.
• Localization: Cytoplasmic
• Specificity: This reacts with prostatic acid phosphatase. It stains prostatic epithelial cells as well as secretion and concretions in the ducts of the prostate.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PSAP
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
• Application Notes: IHC: This antibody may be diluted to a titer of 1:50-1:200 in an ABC method. Suggested incubation period of 30-60 minutes at room temperature. Depending upon the fixation conditions and the staining system employed.
• Control:

  PSAP Overexpression Lysate

Reactivity Notes

Cross-reacts with Human. Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS with BSA
• Preservative: Sodium Azide
• Purity: Protein A purified

Alternate Names for PSAP Antibody

• FLJ00245
• GLBA
• proactivator polypeptide
• prosaposin
• PSAP
• SAP1
• SAP1MGC110993
• sphingolipid activator protein-1

Background

Prostatic acid phosphatase is one of the two antigenic markers of prostatic carcinoma, the other being prostate specific antigen. It belongs to the kallikrein family of serine proteases and is suggested to act as a hydrolase to split phospharyl choline in semen and as a transferase. This antibody does not inhibit the enzymatic activity of PSAP. It reacts with non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no cross reaction with other phosphatases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PSAP
• Entrez:
  • 5660(Human)