PSAP Products

Antibodies
PSAP Antibody (4D5F4)
PSAP Antibody (4D5F4)
NBP2-37422
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
PSAP Antibody
PSAP Antibody
NBP1-83363
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PSAP Antibody [Unconjugated]
PSAP Antibody [Unconjugated]
AF8520
Species: Hu
Applications: WB, ICC
Host: Rabbit Polyclonal
Antibody Pairs
PSAP Antibody Pair
PSAP Antibody Pair
H00005660-PW1
Species: Hu
Applications: WB, IP
PSAP Antibody Pair
PSAP Antibody Pair
H00005660-PW2
Species: Hu
Applications: WB, IP
PSAP Antibody Pair
PSAP Antibody Pair
H00005660-AP11
Species: Hu
Applications: S-ELISA
Lysates
PSAP Overexpression Lysate (N ...
PSAP Overexpression Lysate (Native)
NBL1-14854
Applications: WB
PSAP Overexpression Lysate (N ...
PSAP Overexpression Lysate (Native)
NBL1-14855
Applications: WB
PSAP Overexpression Lysate (N ...
PSAP Overexpression Lysate (Native)
NBP2-08370
Applications: WB
Proteins
Recombinant Human PSAP Protei ...
Recombinant Human PSAP Protein
H00005660-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human PSAP Protei ...
Recombinant Human PSAP Protein
H00005660-P02
Species: Hu
Applications: WB, ELISA, PA
PSAP Recombinant Protein Anti ...
PSAP Recombinant Protein Antigen
NBP1-83363PEP
Species: Hu
Applications: AC
RNAi
PSAP RNAi
PSAP RNAi
H00005660-R01
Species: Hu
Applications: RNAi, RNAi SP
PSAP RNAi
PSAP RNAi
H00005660-R03
Species: Hu
Applications: RNAi, RNAi SP
PSAP RNAi
PSAP RNAi
H00005660-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D, which are similar to each other and are sphingolipid hydrolase activator proteins. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in PSAP gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 5660
Alternate Names
  • proactivator polypeptide
  • GLBA
  • sphingolipid activator protein-1
  • SAP1MGC110993
  • FLJ00245
  • prosaposin

Research Areas for PSAP

Find related products by research area and learn more about each of the different research areas below.

Cancer

Bioinformatics Tool for PSAP

Discover related pathways, diseases and genes to PSAP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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