PRL-3/PTP4A3 Antibody - BSA Free

Western Blot: PRL-3/PTP4A3 Antibody [NBP2-93734] - Analysis of extracts of Mouse skeletal muscle, using PTP4A3 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.

Immunohistochemistry-Paraffin: PRL-3/PTP4A3 Antibody [NBP2-93734] - Paraffin-embedded human gastric cancer using PRL-3/PTP4A3 .

• Reactivity: Hu, Mu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PRL-3/PTP4A3 Antibody - BSA Free Summary

• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-148 of human PTP4A3 (NP_009010.2). MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PTP4A3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500 - 1:1000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for PRL-3/PTP4A3 Antibody - BSA Free

• PRL3
• PRL-3
• PRL3EC 3.1.3.48
• PRL-3potentially prenylated protein tyrosine phosphatase
• PRL-Rprotein tyrosine phosphatase type IVA 3
• protein tyrosine phosphatase type IVA, member 3
• Protein-tyrosine phosphatase 4a3
• Protein-tyrosine phosphatase of regenerating liver 3
• PTP4A3

Background

PRL-3 is encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTP4A3