PRL-3/PTP4A3 Products

Description

PRL-3 is encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.

Bioinformatics

Entrez	11156 Human 19245 Mouse
Uniprot	AAH03105 Human NM_007079 Human NP_009010 Human NP_009010.2 Human NP_116000 Human O75365 Human
Product By Gene ID	11156
Alternate Names	PRL3EC 3.1.3.48 PRL-3potentially prenylated protein tyrosine phosphatase PRL-Rprotein tyrosine phosphatase type IVA 3 protein tyrosine phosphatase type IVA, member 3 Protein-tyrosine phosphatase 4a3 Protein-tyrosine phosphatase of regenerating liver 3

Research Areas for PRL-3/PTP4A3

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Protein Phosphatase