PRL-2/PTP4A2 Antibody (SR2538)

Western Blot: PRL-2/PTP4A2 Antibody (SR2538) [NBP3-27804] - Western blot analysis of Hela, A549, HL-60 lysates

• Reactivity: Hu
• Applications: WB, IP
• Clone: SR2538
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

PRL-2/PTP4A2 Antibody (SR2538) Summary

• Description: Novus Biologicals Rabbit PRL-2/PTP4A2 Antibody (SR2538) (NBP3-27804) is a recombinant monoclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthetic peptide of human PRL-2/PTP4A2 (Uniprot #: Q12974)
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: PTP4A2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1:20
  • Western Blot 1:500-1:1000
• Theoretical MW: 19 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
• Preservative: 0.01% Sodium Azide
• Purity: Affinity purified

Alternate Names for PRL-2/PTP4A2 Antibody (SR2538)

• EC 3.1.3.48
• HH13
• HH7-2
• HU-PP-1
• HU-PP-1HH13
• OV-1
• OV-1PTP4A
• PRL2
• PRL-2
• PRL-2HH7-2
• PRL2protein tyrosine phosphatase IVA
• protein tyrosine phosphatase IVA2
• protein tyrosine phosphatase type IVA 2
• protein tyrosine phosphatase type IVA, member 2
• Protein-tyrosine phosphatase 4a2
• Protein-tyrosine phosphatase of regenerating liver 2
• PTP(CAAXII)
• PTP4A2
• PTPCAAX2
• PTPCAAX2phosphatase of regenerating liver 2
• ptp-IV1a
• ptp-IV1b

Background

PTP4A2 is encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants that encode two distinct isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTP4A2