PRL-2/PTP4A2 Products

Description

PTP4A2 is encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants that encode two distinct isoforms have been described. [provided by RefSeq]

Bioinformatics

Entrez	8073 Human
Uniprot	AF208850 Human NM_080391 Human NP_536316 Human NP_536316.1 Human
Product By Gene ID	8073
Alternate Names	EC 3.1.3.48 HU-PP-1HH13 OV-1PTP4A PRL-2HH7-2 PRL2protein tyrosine phosphatase IVA protein tyrosine phosphatase IVA2 protein tyrosine phosphatase type IVA 2 protein tyrosine phosphatase type IVA, member 2 Protein-tyrosine phosphatase 4a2 Protein-tyrosine phosphatase of regenerating liver 2 PTP(CAAXII) PTPCAAX2phosphatase of regenerating liver 2 ptp-IV1a ptp-IV1b