Recombinant Human PRAT4A/TNRC5 Protein

Product Discontinued

Recombinant Human PRAT4A/TNRC5 Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 31-278 of Human PRAT4A/TNRC5
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSGPSQAGA EENDWVRLPS KCEVCKYVAV ELKSAFEETG KTKEVIGTGY GILDQKASGV KYTKSDLRLI EVTETICKRL LDYSLHKERT GSNRFAKGMS ETFETLHNLV HKGVKVVMDI PYELWNETSA EVADLKKQCD VLVEEFEEVI EDWYRNHQEE DLTEFLCANH VLKGKDTSCL AEQWSGKKGD TAALGGKKSK KKSSRAKAAG GRSSSSKQRK ELGGLEGDPS PEEDEGIQKA SPLTHSPPDE L

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: CNPY3
• Purity: >85%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 29.9 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 10% glycerol, 1 mM DTT
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >85%, by SDS-PAGE

Alternate Names for Recombinant Human PRAT4A/TNRC5 Protein

• CAG4A
• canopy 3 homolog (zebrafish)
• CNPY3
• CTG4A
• ERDA5
• ERDA5CTG repeat protein 4a
• Expanded repeat-domain protein CAG/CTG 5
• PRAT4A
• PRAT4ACAG repeat containing
• Protein associated with TLR4
• protein associated with Toll-like receptor 4A
• protein canopy homolog 3
• TNRC5
• TNRC5expanded repeat domain, CAG/CTG 5
• trinucleotide repeat containing 5
• Trinucleotide repeat-containing gene 5 protein

Background

Canopy 3 homolog, also known as CNPY3, is Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. This protein is required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, CNPY3i s required for both innate and adaptive immune responses. Recombinant human CNPY3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CNPY3