PON2 Antibody (SR3802) - BSA Free

Western Blot: PON2 Antibody (SR3802) [NBP3-27800] - Western blot analysis of PON2 expression in HeLa cell lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC, IP
• Clone: SR3802
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PON2 Antibody (SR3802) - BSA Free Summary

• Description: Novus Biologicals Rabbit PON2 Antibody (SR3802) - BSA Free (NBP3-27800) is a recombinant monoclonal antibody validated for use in IHC, WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human PON2 (Uniprot #: Q15165)
• Specificity: Detects endogenous levels of total PON2
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: PON2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50-1:200
  • Immunoprecipitation 1:50
  • Western Blot 1:1000-1:5000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 150mM NaCl, 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for PON2 Antibody (SR3802) - BSA Free

• A-esterase 2
• Aromatic esterase 2
• EC 3.1.1.2
• EC 3.1.1.81
• paraoxonase 2
• paraoxonase nirs
• PON 2
• PON2
• Serum Aryldialkylphosphatase 2
• serum paraoxonase/arylesterase 2

Background

PON2 encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PON2