PON1 Antibody (NBP2-19893)

Images

 
Western Blot: PON1 Antibody [NBP2-19893] -. Human tissue extracts (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with PON1 antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: PON1 Antibody [NBP2-19893] - Paraffin-embedded mouse liver. PON1 antibody diluted at 1:500.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

PON1 Antibody Summary

Immunogen
Full length human PON1 Recombinant protein.
Localization
Secreted; extracellular space
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PON1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Pig (81%), Rabbit (81%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PON1 Antibody

  • A-esterase 1
  • Aromatic esterase 1
  • arylesterase B-type
  • EC 3.1.1.2
  • EC 3.1.1.81
  • EC 3.1.8.1
  • ESA
  • ESAesterase A
  • K-45
  • MVCD5
  • paraoxonase 1
  • PON 1
  • PON1
  • PONparaoxonase B-type
  • serum aryldiakylphosphatase
  • Serum aryldialkylphosphatase 1
  • serum paraoxonase/arylesterase 1

Background

The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PON1
Entrez
Uniprot