Podoplanin Antibody (8.1.1) [DyLight 405]


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Product Details

Reactivity Mu, Hu(-)Species Glossary
Applications WB, Flow, ICC/IF, IHC-Fr, IHC-P
Golden Syrian Hamster
DyLight 405

Podoplanin Antibody (8.1.1) [DyLight 405] Summary

Murine thymic stromal cell lines
Membrane; Single-pass type I membrane protein.
Lymphatic Endothelium Marker
Golden Syrian Hamster
Protein G purified
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  • Western Blot
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Does not cross-react with human.

Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Protein G purified


Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Podoplanin Antibody (8.1.1) [DyLight 405]

  • 36-KD
  • Aggrus
  • Gp36
  • Gp38
  • GP40
  • HT1A-1
  • hT1alpha-1
  • hT1alpha-2
  • lung type I cell membrane associated glycoprotein
  • lung type-I cell membrane-associated glycoprotein (T1A-2)
  • OTS 8
  • OTS8
  • PA2.26 antigen
  • PDPN
  • Podoplanin
  • RANDAM-2
  • T1A
  • T1A-2
  • T1-alpha


Podoplanin (PDPN, Gp38 or Ots8) belongs to family of type-1 transmembrane sialomucin-like glycoproteins and is expressed in various tissues such as keratinocytes, synovial fibroblasts, lymphatic endothelial cells and cancerous cells. Originally identified in glomerular podocytes, PDPN is now considered as one of the most reliable markers for immunodetection of lymphatic endothelium. Its expression has been documented in benign/malignant cancers such as thymoma, osteosarcoma, laryngeal squamous cell carcinoma, odontogenic tumors as well as in CIS (carcinoma in situ)/ SCC (squamous cell carcinoma) of the oral mucosa. PDPN implicates in cellular migration and/or actin cytoskeleton organization, induction of platelet aggregation and is essential to lung cell proliferation as well as alveolus formation postpartum. PDPN expression is up-regulated by pro-inflammatory factors, such as IFN-gamma, TGF-beta, TNF-alpha and IL-1beta; and its mucin-type character has been shown to be associated with its pathophysiological functions including polarized migration of lymphatic endothelial cells as well as in invasion of cancer. PDPN knockout mice show embryonic lethality with respiratory failure and defective development of lymphoid follicles, germinal centers in spleen and lymph node remnants.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB600-1015APC
Biotin Labeled NB600-1015B
DyLight 350 Labeled NB600-1015UV
DyLight 488 Labeled NB600-1015G
DyLight 550 Labeled NB600-1015R
DyLight 650 Labeled NB600-1015C
DyLight 680 Labeled NB600-1015FR
DyLight 755 Labeled NB600-1015IR
FITC Labeled NB600-1015F
HRP Labeled NB600-1015H
PE Labeled NB600-1015PE
PerCP Labeled NB600-1015PCP

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Bioinformatics Tool for Podoplanin Antibody (NB600-1015V)

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Blogs on Podoplanin.

Meningeal lymphatics: recent discovery defying the concept of central nervous system 'immune privilege'
By Jennifer Sokolowski, MD, PhD. Identification and characterization of meningeal lymphaticsThe recent discovery of a lymphatic system in the meninges surrounding the brain and spinal cord has spurred a surge of int...  Read full blog post.

Podoplanin (OST8, Glycoprotein (Gp) 36 or 38, Lung Type I Cell Membrane Associated Glycoprotein)
Podoplanin is a mucin-type 1 transmembrane glycoprotein found in a wide range of tissues. It appears to be differentially expressed in endothelial cells of lymphatic but not blood vessel origin. In normal skin and kidney, podoplanin co-localizes with...  Read full blog post.

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Product PDFs


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Gene Symbol PDPN