Podoplanin Antibody (8.1.1) [DyLight 405]


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Product Details

Reactivity Mu, Hu(-)Species Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-P, IP
Golden Syrian Hamster
Please see the vial label for concentration. If unlisted please contact technical services.

Podoplanin Antibody (8.1.1) [DyLight 405] Summary

Murine thymic stromal cell lines
Membrane; Single-pass type I membrane protein.
Lymphatic Endothelium Marker
Golden Syrian Hamster
Protein G purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 405
DyLight 405 (A=400, E=420)
50mM Sodium Borate
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Protein G purified


  • Western Blot 1:1000-1:2000
  • Flow Cytometry 1:10-1:1000
  • Immunocytochemistry/Immunofluorescence 1-5ug/ml
  • Immunohistochemistry 1:100-1:500
  • Immunohistochemistry-Paraffin 1:100-1:500
  • Immunoprecipitation 1:10-1:500
Application Notes
This Podoplanin (8.1.1) antibody is useful in Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry on paraffin-embedded sections. Electron Microscopy and Immunohistochemistry-Frozen were reported in scientific literature. Immunoprecipitation and Western Blot, where a band can be seen at ~40 kDa. Optimal dilutions/concentrations should be determined by the end user.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
40 kDa

Reactivity Notes

Mouse. Does not cross-react with human.

Alternate Names for Podoplanin Antibody (8.1.1) [DyLight 405]

  • 36-KD
  • Aggrus
  • Gp36
  • Gp38
  • GP40
  • HT1A-1
  • hT1alpha-1
  • hT1alpha-2
  • lung type I cell membrane associated glycoprotein
  • lung type-I cell membrane-associated glycoprotein (T1A-2)
  • OTS 8
  • OTS8
  • PA2.26 antigen
  • PDPN
  • podoplanin
  • RANDAM-2
  • T1A
  • T1A-2
  • T1-alpha


Podoplanin (PDPN, Gp38 or Ots8) belongs to family of type-1 transmembrane sialomucin-like glycoproteins and is expressed in various tissues such as keratinocytes, synovial fibroblasts, lymphatic endothelial cells and cancerous cells. Originally identified in glomerular podocytes, PDPN is now considered as one of the most reliable markers for immunodetection of lymphatic endothelium. Its expression has been documented in benign/malignant cancers such as thymoma, osteosarcoma, laryngeal squamous cell carcinoma, odontogenic tumors as well as in CIS (carcinoma in situ)/ SCC (squamous cell carcinoma) of the oral mucosa. PDPN implicates in cellular migration and/or actin cytoskeleton organization, induction of platelet aggregation and is essential to lung cell proliferation as well as alveolus formation postpartum. PDPN expression is up-regulated by pro-inflammatory factors, such as IFN-gamma, TGF-beta, TNF-alpha and IL-1beta; and its mucin-type character has been shown to be associated with its pathophysiological functions including polarized migration of lymphatic endothelial cells as well as in invasion of cancer. PDPN knockout mice show embryonic lethality with respiratory failure and defective development of lymphoid follicles, germinal centers in spleen and lymph node remnants.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Podoplanin Antibody (NB600-1015V) (0)

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Secondary Antibodies


Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB600-1015APC
Biotin Labeled NB600-1015B
DyLight 350 Labeled NB600-1015UV
DyLight 405LS Labeled NB600-1015V3
DyLight 488 Labeled NB600-1015G
DyLight 550 Labeled NB600-1015R
DyLight 650 Labeled NB600-1015C
DyLight 680 Labeled NB600-1015FR
DyLight 755 Labeled NB600-1015IR
FITC Labeled NB600-1015F
HRP Labeled NB600-1015H
PE Labeled NB600-1015PE
PerCP Labeled NB600-1015PCP

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Blogs on Podoplanin.

Podoplanin (OST8, Glycoprotein (Gp) 36 or 38, Lung Type I Cell Membrane Associated Glycoprotein)
Podoplanin is a mucin-type 1 transmembrane glycoprotein found in a wide range of tissues. It appears to be differentially expressed in endothelial cells of lymphatic but not blood vessel origin. In normal skin and kidney, podoplanin co-localizes with...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol PDPN

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