PMM2/Phosphomannomutase 2 Antibody - BSA Free

Western Blot: PMM2/Phosphomannomutase 2 Antibody [NBP1-33750] - Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 12% SDS PAGE diluted at 1:1000

Immunohistochemistry-Paraffin: PMM2/Phosphomannomutase 2 Antibody [NBP1-33750] - Paraffin-embedded U87 xenograft, using antibody at 1:100 dilution.

• Reactivity: Hu, Mu, Rt, Bv, RM
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PMM2/Phosphomannomutase 2 Antibody - BSA Free Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human PMM2/Phosphomannomutase 2. The exact sequence is proprietary.
• Localization: Cytoplasm
• Predicted Species: Mouse (93%), Rat (95%), Rhesus Macaque (98%), Bovine (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PMM2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 28 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Chicken (86%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for PMM2/Phosphomannomutase 2 Antibody - BSA Free

• CDG1
• CDG1a
• CDGS
• EC 5.4.2.8
• phosphomannomutase 2
• PMM 2

Background

The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: PMM2