PMM2/Phosphomannomutase 2 Antibody

Images

 
Western Blot: PMM2/Phosphomannomutase 2 Antibody [NBP1-33750] - A: Hela B: Hep G2.
Immunohistochemistry-Paraffin: PMM2/Phosphomannomutase 2 Antibody [NBP1-33750] - Paraffin-embedded U87 xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.24 mg/ml

Order Details

PMM2/Phosphomannomutase 2 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human PMM2. The exact sequence is proprietary.
Localization
Cytoplasm
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PMM2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.24 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PMM2/Phosphomannomutase 2 Antibody

  • CDG1
  • CDG1a
  • CDGS
  • EC 5.4.2.8
  • phosphomannomutase 2
  • PMM 2

Background

The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PMM2