PMM2/Phosphomannomutase 2 Products

Antibodies
PMM2/Phosphomannomutase 2 Ant ...
PMM2/Phosphomannomutase 2 Antibody
NBP2-57753
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
PMM2/Phosphomannomutase 2 Ant ...
PMM2/Phosphomannomutase 2 Antibody
NBP1-33750
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
PMM2/Phosphomannomutase 2 Ant ...
PMM2/Phosphomannomutase 2 Antibody...
NBP2-59458
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF
Host: mouse Monoclonal
Antibody Pairs
PMM2/Phosphomannomutase 2 Ant ...
PMM2/Phosphomannomutase 2 Antibody...
H00005373-PW1
Species: Hu
Applications: WB, IP
Lysates
PMM2/Phosphomannomutase 2 Ove ...
PMM2/Phosphomannomutase 2 Overexpr...
H00005373-T01
Species: Hu
Applications: WB
Proteins
PMM2/Phosphomannomutase 2 Rec ...
PMM2/Phosphomannomutase 2 Recombin...
NBP2-57753PEP
Species: Hu
Applications: AC
Recombinant Human PMM2/Phosph ...
Recombinant Human PMM2/Phosphomann...
NBP1-48600
Species: Hu
Applications: PAGE
RNAi
PMM2/Phosphomannomutase 2 RNA ...
PMM2/Phosphomannomutase 2 RNAi
H00005373-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

PMM2, also known as Phosphomannomutase 2, is a 246 amino acid protein that is 28 kDa, catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Studies are being performed on the relationship of this protein to congenital disorder of glycosylation, hydrops fetalis, premature ovarian failure, cerebellar hypoplasia, metabolic disorders, alcohol abuse, intellectual disability, hypertrophic cardiomyopathy, cerebellar ataxia, galactosemia, peripheral neuropathy, hypogonadism, neuropathy, hypotonia, cardiomyopathy, thrombocytopenia, ataxia, alcoholism, and malaria. The PMM2 protein has also shown an interaction with HIST1H4A, HIST1H4B, HIST1H4D, HIST1H4E, HIST1H4C, and over 130 other proteins in synthesis of substrates in N-glycan biosynthesis, asparagine N-linked glycosylation, metabolism of proteins, post-translational protein modification, biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, fructose and mannose metabolism, amino sugar and nucleotide sugar metabolism, GDP-mannose biosynthesis, and colanic acid building blocks biosynthesis pathways.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 5373
Alternate Names
  • PMM 2
  • CDG1A
  • CDGS
  • CDG1
  • CDG1a
  • EC 5.4.2.8
  • phosphomannomutase 2

Research Areas for PMM2/Phosphomannomutase 2

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism

PTMs for PMM2/Phosphomannomutase 2

Learn more about PTMs related to PMM2/Phosphomannomutase 2.

Glycosylation
Phosphorylation
Cleavage
Acylation

Bioinformatics Tool for PMM2/Phosphomannomutase 2

Discover related pathways, diseases and genes to PMM2/Phosphomannomutase 2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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