PHOX2B Antibody (SR1589) - BSA Free

Western Blot: PHOX2B Antibody (SR1589) [NBP3-21890] - Western blot analysis using NBP3-21890 in Neuro-2a cell lysate.

• Reactivity: Hu, Mu
• Applications: WB, ICC/IF, IHC
• Clone: SR1589
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PHOX2B Antibody (SR1589) - BSA Free Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human PHOX2B (Uniprot #: Q99453)
• Specificity: Detects endogenous levels of total PHOX2B
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: PHOX2B
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:100-1:500
  • Immunohistochemistry-Paraffin 1:100-1:500
  • Western Blot 1:500-1:2000
• Theoretical MW: 35 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for PHOX2B Antibody (SR1589) - BSA Free

• NBPhox
• NBPhoxPhox2b
• Neuroblastoma Phox
• paired mesoderm homeobox 2b
• paired mesoderm homeobox protein 2B
• paired-like homeobox 2bNBLST2
• PHOX2B homeodomain protein
• PHOX2B
• PMX2B
• PMX2Bneuroblastoma paired-type homeobox protein

Background

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PHOX2B