PHOX2B Products

Description

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. (provided by RefSeq)

Bioinformatics

Entrez	8929 Human
Product By Gene ID	8929
Alternate Names	NBPHOX NBPhoxPhox2b Neuroblastoma Phox paired mesoderm homeobox 2b paired mesoderm homeobox protein 2B paired-like homeobox 2bNBLST2 PHOX2B homeodomain protein PMX2Bneuroblastoma paired-type homeobox protein

Research Areas for PHOX2B

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Neuroscience