PDGF R beta Antibody (18A2)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF, CyTOF-ready
Clone
18A2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

PDGF R beta Antibody (18A2) Summary

Immunogen
CD140b-transfected NIH 3T3 cells
Specificity
The monoclonal antibody 18A2 recognizes CD140b / PDGF-RB, the 180-190 kDa beta chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative roles.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PDGFRB
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1 - 5 ug/ml
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
  • CyTOF-ready

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
15mM Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for PDGF R beta Antibody (18A2)

  • beta-type platelet-derived growth factor receptor
  • CD140 antigen-like family member B
  • CD140b antigen
  • CD140b
  • EC 2.7.10
  • EC 2.7.10.1
  • JTK12
  • PDGF R beta
  • PDGFR
  • PDGFR1
  • PDGFRB
  • PDGF-R-beta
  • platelet-derived growth factor receptor, beta polypeptide

Background

CD140b / PDGF-RB (platelet-derived growth factor receptor beta) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a / PDGF-RA. Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumours such as medulloblastoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for PDGF R beta Antibody (NBP1-47232). (Showing 1 - 1 of 1 FAQ).

  1. I would like to know the expiry date of the following products: NBP1-47232, NB110-87060, and NBP1-28429
    • We have a 6 month guarantee of our antibodies from the date they are received by your lab. This does not necessarily go off the lot number. The antibodies often can work longer than this date if stored properly, but they cannot be guaranteed.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-47232AF405
Alexa Fluor 488 Labeled NBP1-47232AF488
Alexa Fluor 647 Labeled NBP1-47232AF647
Alexa Fluor 700 Labeled NBP1-47232AF700
Allophycocyanin Labeled NBP1-47232APC
DyLight 350 Labeled NBP1-47232UV
DyLight 405 Labeled NBP1-47232V
DyLight 488 Labeled NBP1-47232G
DyLight 680 Labeled NBP1-47232FR
DyLight 755 Labeled NBP1-47232IR
PE Labeled NBP1-47232PE
PerCP Labeled NBP1-47232PCP

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Bioinformatics

Gene Symbol PDGFRB
Entrez