PDGF R beta Antibody (18A2) - BSA Free

Flow Cytometry: PDGF R beta Antibody (18A2) [NBP1-47232] - Human CD140b / PDGF-RB stable transfectants with anti-CD140b (18A2) APC.

Flow Cytometry: PDGF R beta Antibody (18A2) [NBP1-47232] - Human CD140b / PDGF-RB stable transfectants with anti-CD140b (18A2) purified GAM-APC.

• Reactivity: Hu
• Applications: Flow, ICC/IF, CyTOF-ready
• Clone: 18A2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

PDGF R beta Antibody (18A2) - BSA Free Summary

• Description: Novus Biologicals Mouse PDGF R beta Antibody (18A2) - BSA Free (NBP1-47232) is a monoclonal antibody validated for use in Flow and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: CD140b-transfected NIH 3T3 cells
• Specificity: The monoclonal antibody 18A2 recognizes CD140b / PDGF-RB, the 180-190 kDa beta chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative roles.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PDGFRB
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 1-4 ug/ml
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000
• Application Notes: This antibody is Cytof ready.
• Theoretical MW: 190 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Phosphate buffered saline (PBS), pH 7.4
• Preservative: 15mM Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for PDGF R beta Antibody (18A2) - BSA Free

• beta-type platelet-derived growth factor receptor
• CD140 antigen-like family member B
• CD140b antigen
• CD140b
• EC 2.7.10
• EC 2.7.10.1
• JTK12
• PDGF R beta
• PDGFR
• PDGFR1
• PDGFRB
• PDGF-R-beta
• platelet-derived growth factor receptor, beta polypeptide

Background

CD140b / PDGF-RB (platelet-derived growth factor receptor beta) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a / PDGF-RA. Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumours such as medulloblastoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for PDGF R beta Antibody (NBP1-47232). (Showing 1 - 1 of 1 FAQ).

1. I would like to know the expiry date of the following products: NBP1-47232, NB110-87060, and NBP1-28429
   • We have a 6 month guarantee of our antibodies from the date they are received by your lab. This does not necessarily go off the lot number. The antibodies often can work longer than this date if stored properly, but they cannot be guaranteed.

Bioinformatics

• Gene Symbol: PDGFRB