Park7/DJ-1 Antibody (1E12) - BSA Free

Western Blot: Park7/DJ-1 Antibody (1E12) [NBP2-59407] - Lane 1: Kidney tissue lysates

Immunocytochemistry/Immunofluorescence: Park7/DJ-1 Antibody (1E12) [NBP2-59407] - Analysis of PARK7 in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human PARK7 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green). Analysis of PARK7 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human PARK7 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

• Reactivity: Hu
• Applications: WB, ELISA, Flow, ICC/IF
• Clone: 1E12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Park7/DJ-1 Antibody (1E12) - BSA Free Summary

• Description: Novus Biologicals Mouse Park7/DJ-1 Antibody (1E12) - BSA Free (NBP2-59407) is a monoclonal antibody validated for use in WB, ELISA, Flow and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant human Park7/DJ-1 (1-189aa) purified from E. coli
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: PARK7
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry 1:10-1:1017
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Western Blot 1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 10% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Park7/DJ-1 Antibody (1E12) - BSA Free

• DJ1
• DJ-1
• DJ1FLJ34360
• EC 3.4
• FLJ27376
• FLJ92274
• Oncogene DJ1
• Park7
• Parkinson disease (autosomal recessive, early onset) 7
• Parkinson disease protein 7
• protein DJ-1

Background

PARK7, also known as DJ-1, is a member of the peptidase C56 protein family. The PARK-7 protein is a positive regulator of androgen receptor-dependent transcription. It has also been reported to be a potential sensor for oxidative stress, a redox-sensitive chaperone, and a key protein for preventing neuronal oxidative stress and cell death.

PARK7 is highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, and is detected at slightly lower levels in placenta and brain. The protein is also detected in astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa.

Defects in this gene cause the autosomal recessive neurodegenerative disorder early-onset Parkinson's disease 7.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PARK7