PA2G4/EBP1 Antibody [Unconjugated]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

PA2G4/EBP1 Antibody [Unconjugated] Summary

• Immunogen: E. coli-derived recombinant human PA2G4
  Ser2-Asp394
  Accession # Q9UQ80
• Specificity: Detects human PA2G4 in direct ELISAs and Western blots.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: PA2G4
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PA2G4/EBP1 Antibody [Unconjugated]

• Cell cycle protein p38-2G4 homolog
• EBP1
• ErbB-3 binding protein 1
• ErbB3-binding protein 1
• ErbB3-binding protein Ebp1
• HG4-1
• p38-2G4
• PA2G4
• proliferation-associated 2G4, 38kD
• proliferation-associated 2G4, 38kDa
• proliferation-associated protein 2G4

Background

The human PA2G4 gene encodes an intracellular protein that was also identified as Ebp 1 (ErbB3 binding protein 1). It has effects on cell cycle progression and inhibits proliferation when ectopically expressed in non-immortalized fibroblasts as well as breast cancer and prostate cancer cell lines. PA2G4 shares 56% amino acid similarity with a 42 kDa protein in the fission yeast, Schizosaccharomyces pombe, suggesting a high degree of evolutionary conservation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PA2G4
• Uniprot:
  • Q9UQ80()